How It Works?

DETAIL
Monoclonal antibodies (mAbs) are designed to function in different ways in helping the immune system:

Flagging cancer cells. Cancer cells that are coated in monoclonal antibodies may be more easily detected and targeted for destruction.

Triggering cell-membrane destruction. To trigger an immune system response that destroy the outer membrane of a cancer cell.

Blocking cell growth. To block the connection between a cancer cell and proteins that promote cell growth.

Blocking immune system inhibitors. Certain proteins that bind to immune system cells are regulators that prevent overactivity of the system.

Monoclonal antibodies that bind to these immune system cells give the cancer-fighting cells an opportunity to work with less inhibition.

Directly attacking cancer cells. To attack the cell more directly, even though they were designed for another purpose such as self-destruction when attaching to a cell.

Delivering radiation treatment. Because of a monoclonal antibody's ability to connect with a cancer cell, the antibody can be engineered as a delivery media for other treatments such as transporting the radiation treatment directly to cancer cells and minimize the effect of radiation on healthy cells and so is chemotherapy. 

Binding cancer and immune cells. Some drugs combine two monoclonal antibodies, one that attaches to a cancer cell and one that attaches to a specific immune system cell. This connection may promote immune system attacks on the cancer cells.